The Science Behind Research And Development Strategy
Overview
N-Gene Research Laboratories is developing small molecule-based therapeutics for the treatment of diabetes. The company's lead product candidate BGP-15 restores nitric oxide synthase and inducible heat shock protein expression resulting in correction of damaged mitochondrial and endoplasmic reticulum functions and improved mitochondrial biogenesis. These in turn help in increasing insulin sensitivity. The product has completed Phase 2a clinical trials. The company has also developed another skincare product BGP-15M which has also completed Phase 2 clinical trials.
Technology
N-Gene works on the pharmacological exploitation of the natural defense mechanism of our cells. The lead compound of the development, BGP-15 targets the cellular stress responses, including the heat shock protein and mitochondrial stress responses. Due to the ubiquitous nature of the targeted mechanism BGP-15 resulted in therapeutic effects in wide variety of diseases, including serious diseases without efficient treatment.
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